Spectrophotometric Determination of Isoniazid in Pharmaceutical Preparations Using Oxidative Coupling Reaction with 2,4-dinitrophenylhydrazine

Spectrophotometric Determination of Metronidazole in Pharmaceutical Preparations

A rapid and sensitive spectrophotometric method is proposed for determination of Metronidazole. The method depends on the reduction of Metronidazole molecule with zinc dust and hydrochloric acid flowed by diazotation and coupling with 8-quinolinol to give colored chromogens easily measured spectrophotometrically which has λmax= 437 nm. The experimental conditions were optimized and berr’s law w...

Spectrophotometric Determination of Diclofenac in Pharmaceutical Preparations

Neste trabalho é proposto um método espectrofotométrico modificado para a determinação de diclofenaco em preparações farmacêuticas. Usa-se solução de cobre(II) como reagente, o que leva à formação de um complexo cobre(II)-diclofenaco de cor verde, com máximo de absorção em 680 nm. Foram estudadas as influências: do pH; da concentração de cobre(II); do uso de ácido acético na solução de cobre(II...

Spectrophotometric determination of isoniazid in pure and pharmaceutical formulations.

Spectrophotometric Determination of Thiols in Pure Substances and Pharmaceutical Preparations

A spectrophotometric method for determination of mesna (MA), 6-mercaptopurine (MP), 6-thioguanine (TG), and 6-propyl-2-thiouracil (PTU) has been developed. The method was based on the reaction of thiouracils with N,N-dimethyl-p-phenylenediamine (DMPD) in acidic solution in the presence of the Fe3+ ion, an oxidising agent. Absorbance of the obtained coloured products was measured at the correspo...

A Simple Spectrophotometric Determination of Rebeprazole in Pharmaceutical Preparations

A simple, sensitive spectrophotometric method was developed for the determination of rabeprazole in pure form and for pharmaceutical formulations. In this method 2,3-dichloro-5, 6-dicyano-p-benzoquinone (DDQ) was utilized for determination of rabeprazole forming charge transfer complex with maximum absorbance at λmax 460 nm. Variables affecting the reaction were studied and optimized. Beer’s la...